Smile! Cell lysis and tissue homogenization simplified

Easy to use, fast cell lysis and tissue homogenization for efficient and reproducible sample preparation.

The challenge:

Reproducible and reliable cell lysis and tissue homogenization needs to produce a smooth and easy to pipette homogenate and minimize the possibility of cross-contamination. A specific consideration for proteomics is the release of the maximum number of proteins to make them accessible for the next steps of sample preparation. Additionally, lab space, the requirement for chiller units, and the noise made by some processes can also impact instrument choice.

The solution:

The BeatBox® is a fast and easy to use instrument for up to 96 samples, which completes the homogenization in as little as 10 minutes without sample cross contamination and minimal heat induction. The BeatBox® has a surprisingly small footprint and quiet operation in comparison to traditional tissue processing machines. With the BeatBox®, cell lysis and tissue homogenization can be integrated into the PreOmics® iST sample preparation workflows.

Apply! Simple, streamlined workflows

1. Preparing samples

Cut tissue into appropriate size or volume of cells

2. BeatBox Tissue Add-on Kit

Add your tissue or cells and the LYSE buffer from iST kit family

3. BeatBox your samples

Select the power and time, then press START

4. Digest and clean-up

Continue with step 2 from selected iST workflow

5. MS analysis

Inject and analyze your samples

Results

BeatBox homogenates show the highest protein yields. Reproducibility of protein yields from different tissues were increased by 2.5x using BeatBox

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PreOmics^®'

BeatBox®

values

Smile

Cell lysis and tissue homogenization simplified

Add tissue or cells and lysis buffer; then select your settings in just two clicks for a perfectly homogenized sample
Maximum protein release in 10 minutes
1-50 mg of wet tissue or up to 1e7 cells
Minimize heat induction and the possibility of cross contamination

Relax

Flexibility and efficiency combined

Versatile, it can homogenize multiple tissue and cell types
Optimized programs depending on tissue type
Flexible throughput; 96 well or 24 single tube format
Superior reproducibility

Realize

Next generation technology - today!

Small footprint
>> L 40 x H 26 x W 24 cm - 5kg
>> L 16" x H 10" x W 10" - 12lbs
7" touch screen simplicity
Utilizes PreOmics® Tissue Homogenization kits and GYUTO bead technology
Seamlessly compatible with iST workflows for even greater efficiency

Homogenization for the next generation

BeatBox®

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BeatBox®

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Instrument

Easy to use, fast cell lysis and tissue homogenization for efficient and reproducible sample preparation.

BeatBox®

Request quote

Instrument

Easy to use, fast cell lysis and tissue homogenization for efficient and reproducible sample preparation.

BeatBox®

Request quote

Instrument

Easy to use, fast cell lysis and tissue homogenization for efficient and reproducible sample preparation.

Request quote

BeatBox Tissue Kit 24x

P.O.00128

24-sample kit

$127

108 €

BeatBox Tissue Kit 96x

P.O.00121

96-sample kit

$481

405 €

BeatBox Bead Remover Foil

P.O.00170

10 pieces

$150

130 €

Separation foils for BeatBox Bead Remover

BeatBox Bead Remover

P.O.00169

Accessory

$600

540 €

Removal of all 96 GYUTO beads from the BeatBox Tissue Kit 96x for downstream liquid handling

The PreOmics® products displayed are for visual representation only and may differ from those received

Resources for BeatBox®

BeatBox | Tissue homogenization

BeatBox and iST for FFPE Tissues 96x

BeatBox and iST for FFPE Tissues 8x

BeatBox Tissue Kit 24x

BeatBox Tissue Kit for Cells 96x

BeatBox Tissue Kit 96x

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BeatBox | Expanding the BeatBox for low-input high-throughput targeted metabolomics and lipidomics | Altos Labs

BeatBox | FFPE sample preparation simplified A xylene-free, high-throughput workflow for in-depth tissue proteome analysis

BeatBox Tissue Kit 24x for increased flexibility and input

BeatBox | Evaluation and benchmarking of the BeatBox for high-throughput cell lysis

BeatBox | High-throughput homogenization technique for deeper analysis of multiple mouse tissue proteomes

BeatBox | Tissue homogenization simplified

BeatBox | Unlocking the proteomic potential of FFPE tissues with BeatBox ® and iST: A xylene-free, high-throughput workfow for in-depth proteome analysis | Bruker

BeatBox | Unlocking the proteomic potential of FFPE tissues with BeatBox and iST: A xylene-free, high-throughput workfow for in-depth proteome analysis | Bruker

BeatBox | High-throughput and low-input Metabolomics Lipidomics sample preparation – A new BeatBox application

BeatBox | BeatBox and iST for streamlined FFPE-tissue processing: A xylene-free, robust, and high-throughput sample preparation for in-depth proteomic analysis

BeatBox | N-glycomic identification of novel soft tissue prognostic biomarkers for oral cancers

BeatBox, iST, PreON | A streamlined and automated proteomics sample preparation workflow for targeted protein degrader studies and more

BeatBox, iST | BeatBox and iST for standardized FFPE tissue processing A robust high-throughput xylene-free sample preparation for proteomic analysis

BeatBox | FFPE sample preparation simplified with BeatBox: A xylene-free, high-throughput workflow for in-depth tissue proteome analysis

BeatBox, iST, PreON | Streamlined and semi-automated proteomics pipeline from protein extraction to data analysis by coupling BeatBox, PreON and PaSER platforms

BeatBox, PreON | Streamlined and semi-automated proteomics pipeline from protein extraction to data analysis by coupling BeatBox, PreON and PaSER platforms

BeatBox | High-performance 96-well tissue homogenization and cell lysis on the BeatBox platform improves protein identification

BeatBox | Highly efficient and reproducible sample homogenization for proteomic analysis of various organs up to 50 mg

BeatBox | BeatBox-iST workflow for efficient, high-throughput protein analysis of different cell types

BeatBox | Efficient, reproducible, high-throughput lysis of cells on the BeatBox platform for protein analysis in 96-well plates

BeatBox | Semi-automated, high-throughput homogenization technique for in-depth analysis of tissue proteome

BeatBox | Meet BeatBox: PreOmics revolutionize tissue homogenization

BeatBox | Doubly functionalized magnetic microspheres with immobilized Trypsin and LysC enabling fast, easy and automatable LC-MS sample preparation

BeatBox | Rethink tissue lysis: High-throughput tissue lysis workflow using the BeatBox platform for in-depth proteomic coverage