PreOmics

Technologies for
Clinical Diagnostics

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Technology

Personalized medicine employs accurate measurements of parameters like proteins from cells e.g. biopsies and body fluids like blood plasma or urine. This results in an increased demand for diagnostic products and new technologies for analyses. Mass spectrometry (MS) – based proteomics allows the sensitive and accurate quantification of almost complete proteomes of complex biological fluids and tissues. PreOmics develops Technologies, Assays and consumables to enable and establish MS-based proteomics in research, biomarker discovery and clinical diagnostics.

Plasma Workflow

Publications

  1. Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells.

    Kulak NA, Pichler G, Paron I, Nagaraj N, Mann M.

    Nat Methods. 2014 Mar;11(3):319-24. doi: 10.1038/nmeth.2834. Epub 2014 Feb 2.

  2. The coming age of complete, accurate, and ubiquitous proteomes.

    Mann M, Kulak NA, Nagaraj N, Cox J.

    Mol Cell. 2014 Mar;11(3):319-24. doi: 10.1038/nmeth.2834. Epub 2014 Feb 2.

  3. System-wide perturbation analysis with nearly complete coverage of the yeast proteome by single-shot ultra HPLC runs on a bench top Orbitrap.

    Nagaraj N, Kulak NA, Cox J, Neuhauser N, Mayr K, Hoerning O, Vorm O, Mann M.

    Mol Cell Proteomics. 2012 Mar;11(3):M111.013722. doi: 10.1074/mcp.M111.013722. Epub 2011 Oct 20.

Team

Awards

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Financing and Partner

BayStartUP
BioM
evotec
HelmholtzZentrum München
LMU Klinikum der Universität München
Max-Planck-Innovation
max planck institute of biochemistry
MetaHeps